Use of LetibotulinumtoxinA for Aesthetic Treatment of Asians: A Consensus.

Treatment of wrinkles and dynamic lines using botulinum toxin has been a routine practice for years in aesthetic clinical settings. The effective treatment of wrinkles requires a comprehensive understanding of facial expression muscles and their interactions, the mechanism of action of botulinum toxin, and individual patient preferences. The dose adjustment practice and injection technique of physicians are affected by cultural differences; most Asian patients prefer natural-looking results. This article aims to present an expert consensus on the injection sites, doses, and levels of botulinum toxin for various indications in Asians, in the hope of providing guidance to some clinicians. This consensus paper reviews LetibotulinumtoxinA (Letybo, Hugel Pharma Inc., Seoul, South Korea) for patient evaluation, dosage, and delivery techniques in Asians from the time LetibotulinumtoxinA was approved up to December 2022. Panelists proposed individualized treatment plans for botulinum toxin type A (BTxA) in three aspects of wrinkle removal, contour adjustment, and face lifting in Asians based on their extensive experience and facial anatomy. When using different BTxA, clinicians should start with a conservative dose and carefully individualize the treatment for each patien and adjust it according to the feedback to obtain a higher satisfaction level.