Long non-coding RNA as potential diagnostic markers for acute myeloid leukemia: A systematic review and meta-analysis.

Yenealem SolomonAyenew BerhanAndargachew AlmawTamirat ErsinoShewaneh DamtieTeklehaimanot KirosAlemie FentieErmias Sisay ChanieAnteneh Mengist DessieErmiyas Alemayehu

Published in: Cancer medicine (2024)

This meta-analysis demonstrated that circulating lncRNAs can serve as potential diagnostic markers for AML. High accuracy of diagnosis was observed in non-BMMC lncRNAs, given cutoff value, and the GADPH internal reference gene used. However, further studies with large sample size are required to confirm our results.

Keyphrases

long non coding rna
acute myeloid leukemia
poor prognosis
systematic review
genome wide identification
case control
allogeneic hematopoietic stem cell transplantation
genome wide analysis
human health
genome wide
meta analyses
network analysis
randomized controlled trial
transcription factor