Predictors of Cognitive Performance Among Infants Treated for Brain Tumors: Findings From a Multisite, Prospective, Longitudinal Trial.
Jeanelle S AliJason M AshfordMichelle A SwainLana L HarderBonnie L Carlson-GreenJonathan M MillerJoanna WallaceRyan J KanerCatherine A BillupsArzu Onar-ThomasThomas E MerchantAmar J GajjarHeather M ConklinPublished in: Journal of clinical oncology : official journal of the American Society of Clinical Oncology (2021)
Even before adjuvant therapy, young children with brain tumors experience cognitive difficulties that can affect quality of life. Changes in cognitive functioning over time were dependent on tumor location and surgical factors rather than adjuvant therapy. These findings may serve to guide treatment planning and indicate targets for cognitive monitoring and intervention.