Acromegaly presenting with myelopathy due to ossification of posterior longitudinal ligament: a case report.
Daisuke KamakuraKatsunori FukutakeKazumasa NakamuraShintaro TsugeKeiji HasegawaNaobumi TochigiAkihito WadaTetsuo MikamiHiroshi TakahashiPublished in: BMC musculoskeletal disorders (2021)
We report a case of acromegaly that was detected after the diagnosis of OPLL. The main challenge in acromegaly is delayed in diagnosis. Even in this case, the facial features characteristic of acromegaly had appeared at least 9 years ago. Early diagnosis and treatment of acromegaly improve prognosis and reduce exposure to GH and IGF-1 through early intervention and seem to suppress the progression of ligament ossification. Orthopedic surgeons and neurosurgeons need to keep in mind that acromegaly is associated with bone/joint lesions and ossification of the spinal ligament and should aim to diagnose acromegaly early.