Multidisciplinary lifestyle intervention to manage pancreatic cancer-related cachexia: a case report.
Alice AvanciniIlaria TrestiniDaniela TregnagoAlessandro CavalloMarco BragatoClelia BonaiutoMassimo LanzaMichele MilellaSara PilottoPublished in: Future science OA (2020)
Pancreatic cancer remains an aggressive disease, with a poor prognosis and a high risk of incurring into cachexia. Supportive care, such as exercise, nutritional and psychological support, may be effective in reducing functional loss, psychological distress and improving nutritional status. We report the effect of 12 weeks of multimodal lifestyle intervention in a 55-year-old female, diagnosed with unresectable body/tail pancreatic cancer and metastasis in the liver, bone, lymph node and lung, to counteract cachexia. The multimodal program resulted safe and feasible. Over 12 weeks, considerable improvements were found in body weight, health-related physical fitness, nutritional status, distress scores, anxiety and depression levels. These findings highlight the potential role of integrated supportive interventions to manage metastatic cancer and cancer-induced cachexia.
Keyphrases
- poor prognosis
- body weight
- physical activity
- papillary thyroid
- lymph node
- randomized controlled trial
- quality improvement
- long non coding rna
- pain management
- metabolic syndrome
- squamous cell
- healthcare
- cardiovascular disease
- squamous cell carcinoma
- small cell lung cancer
- weight loss
- high intensity
- gestational age
- palliative care
- neoadjuvant chemotherapy
- locally advanced
- high glucose
- risk assessment
- radiation therapy
- drug induced
- endothelial cells
- early stage
- depressive symptoms
- preterm birth
- human health
- stress induced