Longitudinal structural and metabolic changes in frontotemporal dementia.
Alexandre BejaninGautam TammewarGabe MarxYann CobigoLeonardo IaccarinoJohn KornakAdam M StaffaroniBradford C DickersonBradley F BoeveDavid S KnopmanMaria Luisa Gorno TempiniBruce L MillerWilliam J JagustAdam L BoxerHoward J RosenGil D RabinoviciPublished in: Neurology (2020)
Our findings demonstrated the sensitivity of 18FDG-PET and structural MRI for tracking disease progression in FTD. Both modalities showed highly overlapping patterns of longitudinal change and comparable sample size estimates to detect longitudinal changes in future clinical trials.