Alpha-Synuclein, cyclooxygenase-2 and prostaglandins-EP2 receptors as neuroinflammatory biomarkers of autism spectrum disorders: Use of combined ROC curves to increase their diagnostic values.

Afaf El-AnsaryManan AlhakbanyAbeer AldbassHanan QasemSarah Al-MazidiRamesa Shafi BhatLaila Al-Ayadhi

Published in: Lipids in health and disease (2021)

The present study indicates that measurement of the predictive value of selected biomarkers related to neuroinflammation and lipid metabolism in children with ASD using a ROC curve analysis should lead to a better understanding of the etiological mechanism of ASD and its link with metabolism. This information may facilitate early diagnosis and intervention.

Keyphrases

autism spectrum disorder
intellectual disability
attention deficit hyperactivity disorder
randomized controlled trial
young adults
traumatic brain injury
healthcare
nitric oxide synthase
health information
nitric oxide
fatty acid
brain injury
inflammatory response
subarachnoid hemorrhage