Efficacy and safety of exogenous surfactant therapy in patients under 12 months of age invasively ventilated for severe bronchiolitis (SURFABRON): protocol for a multicentre, randomised, double-blind, controlled, non-profit trial.

Paolo GhiaGiorgio ContiAndrea Michele WolflerSilvia CarlassaraEloisa GittoImmacolata RulliAndrea MoscatelliCamilla MicalizziFabio SavronRaffaella SagrediniGiulia GenoniMarco BinottiFabio CaramelliMonica FaeAndrea PettenazzoValentina StritoniLuigia D'AmatoGeremia Zito MarinosciEdoardo CalderiniStefano Scalia CatenacciAlberto BerardiFrancesco TorcettaEzio BonanomiDaniele BonacinaGiorgio IvaniPierantonio Santuz

Published in: BMJ open (2020)

Clinicaltrials.gov, issue date 22 May 2019. NCT03959384.

Keyphrases

double blind
phase iii
study protocol
placebo controlled
clinical trial
phase ii
randomized controlled trial
intensive care unit
open label
acute respiratory distress syndrome
early onset
cross sectional