Immune-Mediated Diseases from the Point of View of Psychoneuroimmunoendocrinology.
Miguel Ángel OrtegaCielo Garcia-MonteroOscar Fraile-MartínezMiguel Angel Alvarez-MonAna Maria Gómez-LahozGuillermo LaheraJorge Monserrat SanzRoberto Rodriguez-JimenezJavier QuinteroMelchor Alvarez De MonPublished in: Biology (2022)
Immune-mediated inflammatory diseases (IMIDs) represent a large group of diseases (Crohn's, ulcerative colitis, psoriasis, lupus, and rheumatoid arthritis) evidenced by systemic inflammation and multiorgan involvement. IMIDs result in a reduced quality of life and an economic burden for individuals, health care systems, and countries. In this brief descriptive review, we will focus on some of the common biological pathways of these diseases from the point of view of psychoneuroimmunoendocrinology (PNIE). PNIE consists of four medical disciplines (psychology, nervous system, immune system, and endocrine system), which are key drivers behind the health-disease concept that a human being functions as a unit. We examine these drivers and emphasize the need for integrative treatments that addresses the disease from a psychosomatic point of view.
Keyphrases
- healthcare
- rheumatoid arthritis
- ulcerative colitis
- endothelial cells
- disease activity
- oxidative stress
- mental health
- cross sectional
- health information
- ankylosing spondylitis
- induced pluripotent stem cells
- risk assessment
- health insurance
- interstitial lung disease
- pluripotent stem cells
- atopic dermatitis
- hidradenitis suppurativa