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Expression and splicing mediate distinct biological signals.

Søren Helweg DamLars Rønn OlsenKristoffer Vitting-Seerup
Published in: BMC biology (2023)
These findings establish alternative splicing as a major regulator of the human condition and suggest that most contemporary RNA-seq studies likely miss out on critical biological insights. We anticipate our results will contribute to the transition from a gene-centric to an isoform-centric research paradigm.
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