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Efficacy and safety of fostamatinib in refractory immune thrombocytopenia: a meta-analysis from randomized controlled trials.

Songphol TungjitviboonkunNaharuthai BumrungratanayosJedsadakorn JitwimungsanonThanat KheamakulvanichSmuch Siramongkholkarn
Published in: Annals of hematology (2024)
This meta-analysis provides robust evidence supporting the efficacy of fostamatinib in improving platelet counts and achieving therapeutic goals in adults with refractory ITP. However, fostamatinib's safety profile warrants consideration due to higher rates of diarrhea, hypertension, and abnormal liver function tests.
Keyphrases
  • systematic review
  • meta analyses
  • randomized controlled trial
  • blood pressure
  • peripheral blood
  • clostridium difficile
  • clinical trial
  • case control
  • global health
  • public health