Early surgery or conservative management for asymptomatic severe aortic stenosis: Meta-analysis of RECOVERY and AVATAR.
Khalid ChangalPratyush Pavan DevarasettyRachel RoyfmanSpiro VeriaMohammad YassenRohit VyasMario GösslPublished in: Journal of cardiac surgery (2022)
The standard practice for management for asymptomatic severe aortic stenosis with a normal left ventricular systolic function is conservative management with a few exceptions. This practice is challenged by two recent randomized controlled trials (RCT). All the prior data is observational. We performed a meta-analysis of these 2 RCTs to determine if early surgical aortic valve replacement in this patient population is beneficial compared with the standard conservative therapy.
Keyphrases
- aortic stenosis
- aortic valve replacement
- left ventricular
- transcatheter aortic valve replacement
- ejection fraction
- transcatheter aortic valve implantation
- aortic valve
- systematic review
- healthcare
- heart failure
- coronary artery disease
- hypertrophic cardiomyopathy
- acute myocardial infarction
- cardiac resynchronization therapy
- primary care
- randomized controlled trial
- blood pressure
- mitral valve
- early onset
- minimally invasive
- coronary artery bypass
- case report
- big data
- drug induced
- quality improvement
- acute coronary syndrome
- cross sectional
- percutaneous coronary intervention
- machine learning