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All-in-one adeno-associated virus delivery and genome editing by Neisseria meningitidis Cas9 in vivo.

Raed IbraheimChun-Qing SongAamir MirNadia AmraniWen XueErik J Sontheimer
Published in: Genome biology (2018)
Our findings indicate that NmeCas9 can enable the editing of disease-causing loci in vivo, expanding the targeting scope of RNA-guided nucleases.
Keyphrases
  • genome editing
  • crispr cas
  • genome wide
  • cancer therapy
  • gene therapy
  • genome wide association study
  • genome wide association
  • nucleic acid
  • drug delivery
  • dna methylation