All-in-one adeno-associated virus delivery and genome editing by Neisseria meningitidis Cas9 in vivo.
Raed IbraheimChun-Qing SongAamir MirNadia AmraniWen XueErik J SontheimerPublished in: Genome biology (2018)
Our findings indicate that NmeCas9 can enable the editing of disease-causing loci in vivo, expanding the targeting scope of RNA-guided nucleases.