First-in-human imaging using [ 11 C]MDTC: a radiotracer targeting the cannabinoid receptor type 2.
Yong DuJennifer M CoughlinMary Katherine BrosnanAllen ChenLaura K ShinehouseRehab AbdallahMartin A LodgeWilliam B MathewsChen LiuYunkou WuIl MinnPaige FinleyAndrew W HallWojciech G LesniakRobert F DannalsAndrew G HortiMartin G PomperPublished in: European journal of nuclear medicine and molecular imaging (2023)
C]MDTC PET to assess the high expression of the CB2R by activated microglia in human brain.
Keyphrases
- endothelial cells
- pet imaging
- poor prognosis
- high resolution
- binding protein
- inflammatory response
- computed tomography
- induced pluripotent stem cells
- positron emission tomography
- pet ct
- cancer therapy
- pluripotent stem cells
- neuropathic pain
- long non coding rna
- drug delivery
- photodynamic therapy
- fluorescence imaging