Cytoplasmic PPARγ is a marker of poor prognosis in patients with Cox-1 negative primary breast cancers.
Wanting ShaoChristina KuhnDoris MayrNina DitschMagdalena KailuwaitVerena WolfNadia HarbeckSven MahnerUdo JeschkeVincent CavaillèsSophie SixouPublished in: Journal of translational medicine (2020)
Altogether, these data suggest that the relative expression of cytoplasmic PPARγ and Cox-1 may play an important role in oncogenesis and could be defined as a potential prognosis marker to identify specific high risk BC subgroups.