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Comparative analysis of long-term organ damage in patients with systemic lupus erythematosus using belimumab versus standard therapy: a post hoc longitudinal study.

Murray B UrowitzRobert L OhsfeldtRonald C WielageJohn J DeverMehdi ZakerifarYumi AsukaiSulabha RamachandranAshish V Joshi
Published in: Lupus science & medicine (2021)
Using propensity score matching, this highly heterogeneous sample was sufficiently matched to the Toronto Lupus Cohort, suggesting that patients treated with intravenous belimumab may have reduced organ damage progression versus standard therapy alone. This analysis of a large and diverse pooled SLE population was consistent with our previously published US-focused study.
Keyphrases
  • systemic lupus erythematosus
  • disease activity
  • oxidative stress
  • systematic review
  • randomized controlled trial
  • cross sectional
  • rheumatoid arthritis
  • clinical trial
  • bone marrow
  • study protocol
  • phase iii
  • meta analyses