A Concept for Mining Transitive Sequential Patterns from Pancreatic Cancer Patient Journeys.
Jonas HügelJan Janosch SchneiderDaniel Tran OrtegaElla Maria JentschSophia RheinländerNils Hendrik BeyerHossein EstiriChristoph Ammer-HermenauElisabeth HessmannAlexander Otto KönigVolker EllenriederUlrich Saxnull nullPublished in: Studies in health technology and informatics (2024)
Pancreatic cancer, renowned for its aggressive nature and poor prognosis, necessitates the optimization of treatment strategies. The sequence of procedures in clinical trials is critical, such as evaluating the potential benefits of preoperative chemo-radio-therapy for pancreatic cancer. Nevertheless, we might not be aware of other temporal sequences which have an effect on therapy response or the general outcome. Extracting transitive sequential patterns from patients' medical trajectories allows researchers to identify temporal characteristics for complex diseases. We illustrate how such sequential patterns can be discovered and might be utilized in pancreatic cancer research as well as patient care.
Keyphrases
- poor prognosis
- clinical trial
- end stage renal disease
- long non coding rna
- ejection fraction
- healthcare
- newly diagnosed
- chronic kidney disease
- prognostic factors
- photodynamic therapy
- case report
- stem cells
- randomized controlled trial
- peritoneal dialysis
- patient reported
- bone marrow
- phase ii
- climate change
- locally advanced
- smoking cessation