Emerging evidences support safety and effectiveness of WJ-MSCs for treatment of acute radiation syndrome and lung injury after planned or accidental exposure. Additionally, conditioned media collected after culturing WJ-MSCs can also be used for mitigation of radiation dermatitis. Clinical translation of these findings would be possible after careful evaluation of resilience, effectiveness, and molecular mechanism of action of xenogeneic WJ-MSCs in non-human primates.
Keyphrases
- mesenchymal stem cells
- umbilical cord
- liver failure
- randomized controlled trial
- systematic review
- climate change
- endothelial cells
- respiratory failure
- radiation induced
- stem cells
- drug induced
- aortic dissection
- cell therapy
- intensive care unit
- radiation therapy
- single molecule
- social support
- current status
- acute respiratory distress syndrome