Nocebo response in human models of migraine: A systematic review and meta-analysis of randomized, double-blind, placebo-controlled, two-way crossover trials in migraine without aura and healthy volunteers.
Hashmat GhanizadaAfrim IljaziHåkan AshinaThien Phu DoMohammad Al-Mahdi Al-KaragholiFaisal Mohammad AminMessoud AshinaPublished in: Cephalalgia : an international journal of headache (2020)
The nocebo response in randomised, placebo-controlled two-way crossover trials with intravenous infusions of placebo in migraine is negligible. Future studies using human models of migraine can be conducted by assuming a nocebo response rate of 15.5%.