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Comparative effectiveness of biological disease-modifying antirheumatic drugs and Janus kinase inhibitor monotherapy in rheumatoid arthritis.

Akira OnishiHirotaka YamadaWataru YamamotoRyu WatanabeRyota HaraMasaki KatayamaYasutaka OkitaYuichi MaedaHideki AmuroYonsu SonAyaka YoshikawaKenichiro HataMotomu HashimotoJun SaegusaAkio Morinobu
Published in: Rheumatology (Oxford, England) (2023)
In the analysis with IPW to reduce selection bias, IL-6Ri monotherapy was superior to TNFi monotherapy in terms of effectiveness and drug retention. No significant differences were identified between CTLA4Ig, JAKi, and TNFi monotherapy.
Keyphrases
  • combination therapy
  • rheumatoid arthritis
  • open label
  • randomized controlled trial
  • disease activity
  • clinical trial
  • rheumatoid arthritis patients
  • ankylosing spondylitis
  • systemic lupus erythematosus
  • drug induced