Critical disease related to SARS-CoV-2 infection in children from the Amazon region: an observational study.
Emmerson Carlos Franco de FariasManoel Jaime Castro Pavão JúniorSusan C D de SalesLuciana M P P do NascimentoMary de MelloPatricia CarvalhoMaria Teresa TerreriGleice ClementePublished in: BMJ paediatrics open (2023)
This is a multicentre prospective cohort including critically ill children and adolescents, with confirmed critical disease related to SARS-CoV-2, admitted to three tertiary paediatric intensive care units in the Brazilian Amazon, between April 2020 and July 2022. 208 patients were included (median age was 3.5 years). The majority had malnutrition (62%) and comorbidities (60.6%). Mechanical ventilation support, cardiogenic shock and acute respiratory distress syndrome occurred in 47%, 30% and 34.1% of patients, respectively. There were 37 (18%) deaths. A poor outcome of severe COVID-19 and multisystem inflammatory syndrome in children was observed in children and adolescents from the Brazilian Amazon.
Keyphrases
- mechanical ventilation
- acute respiratory distress syndrome
- sars cov
- intensive care unit
- end stage renal disease
- extracorporeal membrane oxygenation
- ejection fraction
- chronic kidney disease
- emergency department
- young adults
- prognostic factors
- clinical trial
- coronavirus disease
- patient reported outcomes
- respiratory syndrome coronavirus
- oxidative stress
- randomized controlled trial
- cross sectional
- respiratory failure