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Motor Neuron Disease Systematic Multi-Arm Adaptive Randomised Trial (MND-SMART): a multi-arm, multi-stage, adaptive, platform, phase III randomised, double-blind, placebo-controlled trial of repurposed drugs in motor neuron disease.

Charis WongRachel S DakinJill WilliamsonJudith NewtonMichelle StevenShuna ColvilleMaria StavrouJenna M GregoryElizabeth ElliottArpan R MehtaJeremy ChatawayRobert J SwinglerRichard Anthony ParkerChristopher J WeirNigel StallardMahesh K B ParmarMalcolm Robert MacLeodSuvankar PalSiddharthan Chandran
Published in: BMJ open (2022)
European Clinical Trials Registry (2019-000099-41); NCT04302870.
Keyphrases
  • double blind
  • clinical trial
  • phase iii
  • open label
  • placebo controlled
  • study protocol
  • phase ii
  • randomized controlled trial
  • high throughput