Siddharthan Chandran

ORCID

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 22

Top Venues

BMJ open

Science advances

The Journal of experimental medicine

Acta neuropathologica communications

University of Edinburgh

University of Edinburgh (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

University of Edinburgh Jul 01 2009

United Kingdom

Professor of Neurology :: Clinical Brain Sciences

Education History

University of Edinburgh

United Kingdom

PHD :: Clinical Brain Sciences

Publications

James Blackstone, Thomas Williams, Jennifer M Nicholas, Ekaterina Bordea, Floriana De Angelis, Alessia Bianchi, Alberto Calvi, Anisha Doshi, Nevin John, Sean Apap Mangion, Charles Wade, Rachel Merry, Gil Barton, Dawn Lyle, Elisabeth Jarman, Don Mahad, Abdullah Shehu, Tarunya Arun, Gavin McDonnell, Ruth Geraldes, Matthew Craner, Charles Hillier, Jeban Ganesalingam, Leonora Fisniku, Jeremy Hobart, Cord Spilker, Neil Robertson, Seema Kalra, Stefano Pluchino, Sreedharan Harikrishnan, Miriam Mattoscio, Timothy Harrower, Carolyn Young, Martin Lee, Suresh Chhetri, Fayyaz Ahmed, David Rog, Eli Silber, Paul Gallagher, Martin Duddy, Agne Straukiene, Richard Nicholas, Claire Rice, Stuart J Nixon, Judy Beveridge, Annie Hawton, Susan Tebbs, Marie Braisher, Gavin Giovannoni, Olga Ciccarelli, John Greenwood, Alan J Thompson, Rachael Maree Hunter, Sue Pavitt, Owen Pearson, Nikos Evangelou, Basil Sharrack, Ian Galea, Siddharthan Chandran, Helen L Ford, Chris Frost, Jeremy Chataway
Evaluating the effectiveness of simvastatin in slowing the progression of disability in secondary progressive multiple sclerosis (MS-STAT2): protocol for a multicentre, randomised controlled, double-blind, phase 3 clinical trial in the UK. BMJ open 14 (9) (2024)
Charis Wong, Jenna M Gregory, Jing Liao, Kieren J Egan, Hanna M Vesterinen, Aimal Ahmad Khan, Mohammed Ma'arij Anwar, Caitlin Beagan, Fraser S Brown, John Cafferkey, Alessandra Cardinali, Jane Yi Chiam, Claire Chiang, Victoria G Collins, Joyce Dormido, Elizabeth Elliott, Peter Foley, Yu Cheng Foo, Lily Fulton-Humble, Angus B Gane, Stella A Glasmacher, Áine Heffernan, Kiran Jayaprakash, Nimesh Jayasuriya, Amina Kaddouri, Jamie Kiernan, Gavin Langlands, D Leighton, Jiaming Liu, James Lyon, Arpan R Mehta, Alyssa Meng, Vivienne Nguyen, Na Hyun Park, Suzanne Quigley, Yousuf Rashid, Andrea Salzinger, Bethany Shiell, Ankur Singh, Tim Soane, Alexandra Thompson, Olaf Tomala, Fergal M Waldron, Bhuvaneish T Selvaraj, Jeremy Chataway, Robert Swingler, Peter Connick, Suvankar Pal, Siddharthan Chandran, Malcolm Robert MacLeod
Systematic, comprehensive, evidence-based approach to identify neuroprotective interventions for motor neuron disease: using systematic reviews to inform expert consensus. BMJ open 13 (2) (2023)
Poulomi Banerjee, Arpan R Mehta, Raja S Nirujogi, James Cooper, Owen G James, Jyoti Nanda, James Longden, Karen Burr, Karina McDade, Andrea Salzinger, Evdokia Paza, Judith Newton, David Story, Suvankar Pal, Colin Smith, Dario R Alessi, Bhuvaneish T Selvaraj, Josef Priller, Siddharthan Chandran
Cell-autonomous immune dysfunction driven by disrupted autophagy in C9orf72 -ALS iPSC-derived microglia contributes to neurodegeneration. Science advances 9 (16) (2023)
Poulomi Banerjee, Arpan R Mehta, Raja S Nirujogi, James Cooper, Owen G James, Jyoti Nanda, James Longden, Karen Burr, Karina McDade, Andrea Salzinger, Evdokia Paza, Judith Newton, David Story, Suvankar Pal, Colin Smith, Dario R Alessi, Bhuvaneish T Selvaraj, Josef Priller, Siddharthan Chandran
Cell-autonomous immune dysfunction driven by disrupted autophagy in C9orf72 -ALS iPSC-derived microglia contributes to neurodegeneration. Science advances 9 (16) (2023)
Poulomi Banerjee, Arpan R Mehta, Raja S Nirujogi, James Cooper, Owen G James, Jyoti Nanda, James Longden, Karen Burr, Karina McDade, Andrea Salzinger, Evdokia Paza, Judith Newton, David Story, Suvankar Pal, Colin Smith, Dario R Alessi, Bhuvaneish T Selvaraj, Josef Priller, Siddharthan Chandran
Cell-autonomous immune dysfunction driven by disrupted autophagy in C9orf72 -ALS iPSC-derived microglia contributes to neurodegeneration. Science advances 9 (16) (2023)
Poulomi Banerjee, Arpan R Mehta, Raja S Nirujogi, James Cooper, Owen G James, Jyoti Nanda, James Longden, Karen Burr, Karina McDade, Andrea Salzinger, Evdokia Paza, Judith Newton, David Story, Suvankar Pal, Colin Smith, Dario R Alessi, Bhuvaneish T Selvaraj, Josef Priller, Siddharthan Chandran
Cell-autonomous immune dysfunction driven by disrupted autophagy in C9orf72 -ALS iPSC-derived microglia contributes to neurodegeneration. Science advances 9 (16) (2023)
Charis Wong, Jenna M Gregory, Jing Liao, Kieren J Egan, Hanna M Vesterinen, Aimal Ahmad Khan, Mohammed Ma'arij Anwar, Caitlin Beagan, Fraser S Brown, John Cafferkey, Alessandra Cardinali, Jane Yi Chiam, Claire Chiang, Victoria G Collins, Joyce Dormido, Elizabeth Elliott, Peter Foley, Yu Cheng Foo, Lily Fulton-Humble, Angus B Gane, Stella A Glasmacher, Áine Heffernan, Kiran Jayaprakash, Nimesh Jayasuriya, Amina Kaddouri, Jamie Kiernan, Gavin Langlands, D Leighton, Jiaming Liu, James Lyon, Arpan R Mehta, Alyssa Meng, Vivienne Nguyen, Na Hyun Park, Suzanne Quigley, Yousuf Rashid, Andrea Salzinger, Bethany Shiell, Ankur Singh, Tim Soane, Alexandra Thompson, Olaf Tomala, Fergal M Waldron, Bhuvaneish T Selvaraj, Jeremy Chataway, Robert Swingler, Peter Connick, Suvankar Pal, Siddharthan Chandran, Malcolm Robert MacLeod
Systematic, comprehensive, evidence-based approach to identify neuroprotective interventions for motor neuron disease: using systematic reviews to inform expert consensus. BMJ open 13 (2) (2023)
Jimmy Beckers, Arun Kumar Tharkeshwar, Laura Fumagalli, Matilde Contardo, Evelien Van Schoor, Raheem Fazal, Dietmar Rudolf Thal, Siddharthan Chandran, Renzo Mancuso, Ludo Van Den Bosch, Philip Van Damme
A toxic gain-of-function mechanism in C9orf72 ALS impairs the autophagy-lysosome pathway in neurons. Acta neuropathologica communications 11 (1) (2023)
Charis Wong, Jenna M Gregory, Jing Liao, Kieren J Egan, Hanna M Vesterinen, Aimal Ahmad Khan, Mohammed Ma'arij Anwar, Caitlin Beagan, Fraser S Brown, John Cafferkey, Alessandra Cardinali, Jane Yi Chiam, Claire Chiang, Victoria G Collins, Joyce Dormido, Elizabeth Elliott, Peter Foley, Yu Cheng Foo, Lily Fulton-Humble, Angus B Gane, Stella A Glasmacher, Áine Heffernan, Kiran Jayaprakash, Nimesh Jayasuriya, Amina Kaddouri, Jamie Kiernan, Gavin Langlands, D Leighton, Jiaming Liu, James Lyon, Arpan R Mehta, Alyssa Meng, Vivienne Nguyen, Na Hyun Park, Suzanne Quigley, Yousuf Rashid, Andrea Salzinger, Bethany Shiell, Ankur Singh, Tim Soane, Alexandra Thompson, Olaf Tomala, Fergal M Waldron, Bhuvaneish T Selvaraj, Jeremy Chataway, Robert Swingler, Peter Connick, Suvankar Pal, Siddharthan Chandran, Malcolm Robert MacLeod
Systematic, comprehensive, evidence-based approach to identify neuroprotective interventions for motor neuron disease: using systematic reviews to inform expert consensus. BMJ open 13 (2) (2023)
Charis Wong, Jenna M Gregory, Jing Liao, Kieren J Egan, Hanna M Vesterinen, Aimal Ahmad Khan, Mohammed Ma'arij Anwar, Caitlin Beagan, Fraser S Brown, John Cafferkey, Alessandra Cardinali, Jane Yi Chiam, Claire Chiang, Victoria G Collins, Joyce Dormido, Elizabeth Elliott, Peter Foley, Yu Cheng Foo, Lily Fulton-Humble, Angus B Gane, Stella A Glasmacher, Áine Heffernan, Kiran Jayaprakash, Nimesh Jayasuriya, Amina Kaddouri, Jamie Kiernan, Gavin Langlands, D Leighton, Jiaming Liu, James Lyon, Arpan R Mehta, Alyssa Meng, Vivienne Nguyen, Na Hyun Park, Suzanne Quigley, Yousuf Rashid, Andrea Salzinger, Bethany Shiell, Ankur Singh, Tim Soane, Alexandra Thompson, Olaf Tomala, Fergal M Waldron, Bhuvaneish T Selvaraj, Jeremy Chataway, Robert Swingler, Peter Connick, Suvankar Pal, Siddharthan Chandran, Malcolm Robert MacLeod
Systematic, comprehensive, evidence-based approach to identify neuroprotective interventions for motor neuron disease: using systematic reviews to inform expert consensus. BMJ open 13 (2) (2023)
Poulomi Banerjee, Arpan R Mehta, Raja S Nirujogi, James Cooper, Owen G James, Jyoti Nanda, James Longden, Karen Burr, Karina McDade, Andrea Salzinger, Evdokia Paza, Judith Newton, David Story, Suvankar Pal, Colin Smith, Dario R Alessi, Bhuvaneish T Selvaraj, Josef Priller, Siddharthan Chandran
Cell-autonomous immune dysfunction driven by disrupted autophagy in C9orf72 -ALS iPSC-derived microglia contributes to neurodegeneration. Science advances 9 (16) (2023)
Charis Wong, Jenna M Gregory, Jing Liao, Kieren J Egan, Hanna M Vesterinen, Aimal Ahmad Khan, Mohammed Ma'arij Anwar, Caitlin Beagan, Fraser S Brown, John Cafferkey, Alessandra Cardinali, Jane Yi Chiam, Claire Chiang, Victoria G Collins, Joyce Dormido, Elizabeth Elliott, Peter Foley, Yu Cheng Foo, Lily Fulton-Humble, Angus B Gane, Stella A Glasmacher, Áine Heffernan, Kiran Jayaprakash, Nimesh Jayasuriya, Amina Kaddouri, Jamie Kiernan, Gavin Langlands, D Leighton, Jiaming Liu, James Lyon, Arpan R Mehta, Alyssa Meng, Vivienne Nguyen, Na Hyun Park, Suzanne Quigley, Yousuf Rashid, Andrea Salzinger, Bethany Shiell, Ankur Singh, Tim Soane, Alexandra Thompson, Olaf Tomala, Fergal M Waldron, Bhuvaneish T Selvaraj, Jeremy Chataway, Robert Swingler, Peter Connick, Suvankar Pal, Siddharthan Chandran, Malcolm Robert MacLeod
Systematic, comprehensive, evidence-based approach to identify neuroprotective interventions for motor neuron disease: using systematic reviews to inform expert consensus. BMJ open 13 (2) (2023)
Charis Wong, Jenna M Gregory, Jing Liao, Kieren J Egan, Hanna M Vesterinen, Aimal Ahmad Khan, Mohammed Ma'arij Anwar, Caitlin Beagan, Fraser S Brown, John Cafferkey, Alessandra Cardinali, Jane Yi Chiam, Claire Chiang, Victoria G Collins, Joyce Dormido, Elizabeth Elliott, Peter Foley, Yu Cheng Foo, Lily Fulton-Humble, Angus B Gane, Stella A Glasmacher, Áine Heffernan, Kiran Jayaprakash, Nimesh Jayasuriya, Amina Kaddouri, Jamie Kiernan, Gavin Langlands, D Leighton, Jiaming Liu, James Lyon, Arpan R Mehta, Alyssa Meng, Vivienne Nguyen, Na Hyun Park, Suzanne Quigley, Yousuf Rashid, Andrea Salzinger, Bethany Shiell, Ankur Singh, Tim Soane, Alexandra Thompson, Olaf Tomala, Fergal M Waldron, Bhuvaneish T Selvaraj, Jeremy Chataway, Robert Swingler, Peter Connick, Suvankar Pal, Siddharthan Chandran, Malcolm Robert MacLeod
Systematic, comprehensive, evidence-based approach to identify neuroprotective interventions for motor neuron disease: using systematic reviews to inform expert consensus. BMJ open 13 (2) (2023)
Poulomi Banerjee, Arpan R Mehta, Raja S Nirujogi, James Cooper, Owen G James, Jyoti Nanda, James Longden, Karen Burr, Karina McDade, Andrea Salzinger, Evdokia Paza, Judith Newton, David Story, Suvankar Pal, Colin Smith, Dario R Alessi, Bhuvaneish T Selvaraj, Josef Priller, Siddharthan Chandran
Cell-autonomous immune dysfunction driven by disrupted autophagy in C9orf72 -ALS iPSC-derived microglia contributes to neurodegeneration. Science advances 9 (16) (2023)
Charis Wong, Jenna M Gregory, Jing Liao, Kieren J Egan, Hanna M Vesterinen, Aimal Ahmad Khan, Mohammed Ma'arij Anwar, Caitlin Beagan, Fraser S Brown, John Cafferkey, Alessandra Cardinali, Jane Yi Chiam, Claire Chiang, Victoria G Collins, Joyce Dormido, Elizabeth Elliott, Peter Foley, Yu Cheng Foo, Lily Fulton-Humble, Angus B Gane, Stella A Glasmacher, Áine Heffernan, Kiran Jayaprakash, Nimesh Jayasuriya, Amina Kaddouri, Jamie Kiernan, Gavin Langlands, D Leighton, Jiaming Liu, James Lyon, Arpan R Mehta, Alyssa Meng, Vivienne Nguyen, Na Hyun Park, Suzanne Quigley, Yousuf Rashid, Andrea Salzinger, Bethany Shiell, Ankur Singh, Tim Soane, Alexandra Thompson, Olaf Tomala, Fergal M Waldron, Bhuvaneish T Selvaraj, Jeremy Chataway, Robert Swingler, Peter Connick, Suvankar Pal, Siddharthan Chandran, Malcolm Robert MacLeod
Systematic, comprehensive, evidence-based approach to identify neuroprotective interventions for motor neuron disease: using systematic reviews to inform expert consensus. BMJ open 13 (2) (2023)
Poulomi Banerjee, Arpan R Mehta, Raja S Nirujogi, James Cooper, Owen G James, Jyoti Nanda, James Longden, Karen Burr, Karina McDade, Andrea Salzinger, Evdokia Paza, Judith Newton, David Story, Suvankar Pal, Colin Smith, Dario R Alessi, Bhuvaneish T Selvaraj, Josef Priller, Siddharthan Chandran
Cell-autonomous immune dysfunction driven by disrupted autophagy in C9orf72 -ALS iPSC-derived microglia contributes to neurodegeneration. Science advances 9 (16) (2023)
Charis Wong, Jenna M Gregory, Jing Liao, Kieren J Egan, Hanna M Vesterinen, Aimal Ahmad Khan, Mohammed Ma'arij Anwar, Caitlin Beagan, Fraser S Brown, John Cafferkey, Alessandra Cardinali, Jane Yi Chiam, Claire Chiang, Victoria G Collins, Joyce Dormido, Elizabeth Elliott, Peter Foley, Yu Cheng Foo, Lily Fulton-Humble, Angus B Gane, Stella A Glasmacher, Áine Heffernan, Kiran Jayaprakash, Nimesh Jayasuriya, Amina Kaddouri, Jamie Kiernan, Gavin Langlands, D Leighton, Jiaming Liu, James Lyon, Arpan R Mehta, Alyssa Meng, Vivienne Nguyen, Na Hyun Park, Suzanne Quigley, Yousuf Rashid, Andrea Salzinger, Bethany Shiell, Ankur Singh, Tim Soane, Alexandra Thompson, Olaf Tomala, Fergal M Waldron, Bhuvaneish T Selvaraj, Jeremy Chataway, Robert Swingler, Peter Connick, Suvankar Pal, Siddharthan Chandran, Malcolm Robert MacLeod
Systematic, comprehensive, evidence-based approach to identify neuroprotective interventions for motor neuron disease: using systematic reviews to inform expert consensus. BMJ open 13 (2) (2023)
James William L Brown, Ferran Prados Carrasco, Daniel R Altmann, Baris Kanber, Jonathan Stutters, Nicholas G Cunniffe, Joanne Louise Jones, Zoya G Georgieva, Edward J Needham, Cyrus Daruwalla, Claudia Gandini Wheeler-Kingshott, Peter Connick, Siddharthan Chandran, Robin Franklin, David MacManus, Rebecca Samson, Alasdair J Coles, Declan T Chard
Remyelination varies between and within lesions in multiple sclerosis following bexarotene. Annals of clinical and translational neurology 9 (10) (2022)
Patrick K A Kearns, Sarah J Martin, Jessie Chang, Rozanna Meijboom, Elizabeth N York, Yingdi Chen, Christine Weaver, Amy Stenson, Katarzyna Hafezi, Stacey Thomson, Elizabeth Freyer, Lee Murphy, Adil Harroud, Peter Foley, David Hunt, Margaret McLeod, Jonathon O'Riordan, F J Carod-Artal, Niall J J MacDougall, Sergio E Baranzini, Adam D Waldman, Peter Connick, Siddharthan Chandran
FutureMS cohort profile: a Scottish multicentre inception cohort study of relapsing-remitting multiple sclerosis. BMJ open 12 (6) (2022)
Charis Wong, Rachel S Dakin, Jill Williamson, Judith Newton, Michelle Steven, Shuna Colville, Maria Stavrou, Jenna M Gregory, Elizabeth Elliott, Arpan R Mehta, Jeremy Chataway, Robert J Swingler, Richard Anthony Parker, Christopher J Weir, Nigel Stallard, Mahesh K B Parmar, Malcolm Robert MacLeod, Suvankar Pal, Siddharthan Chandran
Motor Neuron Disease Systematic Multi-Arm Adaptive Randomised Trial (MND-SMART): a multi-arm, multi-stage, adaptive, platform, phase III randomised, double-blind, placebo-controlled trial of repurposed drugs in motor neuron disease. BMJ open 12 (7) (2022)
David A D Munro, Barry M Bradford, Samanta A Mariani, David W Hampton, Chris S Vink, Siddharthan Chandran, David A Hume, Clare Pridans, Josef Priller
CNS macrophages differentially rely on an intronic Csf1r enhancer for their development. Development (Cambridge, England) 147 (23) (2020)
Zuzana Krejciova, James Alibhai, Chen Zhao, Robert Krencik, Nina M Rzechorzek, Erik M Ullian, Jean Manson, James W Ironside, Mark W Head, Siddharthan Chandran
Human stem cell-derived astrocytes replicate human prions in a PRNP genotype-dependent manner. The Journal of experimental medicine 214 (12) (2017)

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Publication Activity (10 Years)

Top Topics

Top Venues

Siddharthan Chandran