Absence of ABL1 exon 2-encoded SH3 residues in BCR::ABL1 destabilizes the autoinhibited kinase conformation and confers resistance to asciminib.
Ariel Leyte-VidalRosaAnna DeFilippisIan R OuthwaiteIsabelle KwanJi Young LeeCarlyn LeavittKaeli B MillerDelphine ReaAziz M RangwalaKevin LouSuhana PatelAilin AlvarezKevan M ShokatIvet BaharMarkus A SeeligerNeil P ShahPublished in: Leukemia (2024)