Aziz M Rangwala

Publication Activity (10 Years)

Years Active: 2021-2024
Publications (10 Years): 9

Top Topics

Tyrosine Kinase

Endoplasmic Reticulum

Crystal Structure

Top Venues

Nature chemical biology

Proceedings of the National Academy of Sciences of the United States of America

Molecular & cellular oncology

This page only lists publications with an associated author ORCID identifier.

Publications

Ariel Leyte-Vidal, RosaAnna DeFilippis, Ian R Outhwaite, Isabelle Kwan, Ji Young Lee, Carlyn Leavitt, Kaeli B Miller, Delphine Rea, Aziz M Rangwala, Kevin Lou, Suhana Patel, Ailin Alvarez, Kevan M Shokat, Ivet Bahar, Markus A Seeliger, Neil P Shah
Absence of ABL1 exon 2-encoded SH3 residues in BCR::ABL1 destabilizes the autoinhibited kinase conformation and confers resistance to asciminib. Leukemia (2024)
Ariel Leyte-Vidal, RosaAnna DeFilippis, Ian R Outhwaite, Isabelle Kwan, Ji Young Lee, Carlyn Leavitt, Kaeli B Miller, Delphine Rea, Aziz M Rangwala, Kevin Lou, Suhana Patel, Ailin Alvarez, Kevan M Shokat, Ivet Bahar, Markus A Seeliger, Neil P Shah
Absence of ABL1 exon 2-encoded SH3 residues in BCR::ABL1 destabilizes the autoinhibited kinase conformation and confers resistance to asciminib. Leukemia 38 (9) (2024)
Ariel Leyte-Vidal, RosaAnna DeFilippis, Ian R Outhwaite, Isabelle Kwan, Ji Young Lee, Carlyn Leavitt, Kaeli B Miller, Delphine Rea, Aziz M Rangwala, Kevin Lou, Suhana Patel, Ailin Alvarez, Kevan M Shokat, Ivet Bahar, Markus A Seeliger, Neil P Shah
Absence of ABL1 exon 2-encoded SH3 residues in BCR::ABL1 destabilizes the autoinhibited kinase conformation and confers resistance to asciminib. Leukemia 38 (9) (2024)
Ariel Leyte-Vidal, RosaAnna DeFilippis, Ian R Outhwaite, Isabelle Kwan, Ji Young Lee, Carlyn Leavitt, Kaeli B Miller, Delphine Rea, Aziz M Rangwala, Kevin Lou, Suhana Patel, Ailin Alvarez, Kevan M Shokat, Ivet Bahar, Markus A Seeliger, Neil P Shah
Absence of ABL1 exon 2-encoded SH3 residues in BCR::ABL1 destabilizes the autoinhibited kinase conformation and confers resistance to asciminib. Leukemia 38 (9) (2024)
Ariel Leyte-Vidal, RosaAnna DeFilippis, Ian R Outhwaite, Isabelle Kwan, Ji Young Lee, Carlyn Leavitt, Kaeli B Miller, Delphine Rea, Aziz M Rangwala, Kevin Lou, Suhana Patel, Ailin Alvarez, Kevan M Shokat, Ivet Bahar, Markus A Seeliger, Neil P Shah
Absence of ABL1 exon 2-encoded SH3 residues in BCR::ABL1 destabilizes the autoinhibited kinase conformation and confers resistance to asciminib. Leukemia 38 (9) (2024)
Aziz M Rangwala, Benedict-Tilmann Berger, Matthew B Robers, Stefan Knapp, Markus A Seeliger
Resistance to kinase inhibition through shortened target engagement. Molecular & cellular oncology 9 (1) (2022)
Alexander A Peterson, Aziz M Rangwala, Manish K Thakur, Patrick S Ward, Christie Hung, Ian R Outhwaite, Alix I Chan, Dmitry L Usanov, Vamsi K Mootha, Markus A Seeliger, David R Liu
Discovery and molecular basis of subtype-selective cyclophilin inhibitors. Nature chemical biology 18 (11) (2022)
Aziz M Rangwala, Victoria R Mingione, George Georghiou, Markus A Seeliger
Kinases on Double Duty: A Review of UniProtKB Annotated Bifunctionality within the Kinome. Biomolecules 12 (5) (2022)
Agatha Lyczek, Benedict-Tilman Berger, Aziz M Rangwala, YiTing Paung, Jessica Tom, Hannah Philipose, Jiaye Guo, Steven K Albanese, Matthew B Robers, Stefan Knapp, John D Chodera, Markus A Seeliger
Mutation in Abl kinase with altered drug-binding kinetics indicates a novel mechanism of imatinib resistance. Proceedings of the National Academy of Sciences of the United States of America 118 (46) (2021)