Central Obesity in Axial Spondyloarthritis: The Missing Link to Understanding Worse Outcomes in Women?
Sinead MaguireFiona WilsonPhil GallagherFinbar D O'SheaPublished in: The Journal of rheumatology (2022)
There was a high prevalence of central obesity as assessed by the WHR in axSpA, most notably among women with axSpA. This modifiable comorbidity was significantly associated with worse quality of life, greater impairment of functional ability, and a trend toward worse disease activity. Regular use of the WHR to screen for central obesity as part of an axSpA assessment would provide an opportunity for prompt identification and intervention for at-risk patients.
Keyphrases
- disease activity
- insulin resistance
- metabolic syndrome
- weight loss
- rheumatoid arthritis
- systemic lupus erythematosus
- ankylosing spondylitis
- high fat diet induced
- type diabetes
- weight gain
- end stage renal disease
- rheumatoid arthritis patients
- polycystic ovary syndrome
- ejection fraction
- randomized controlled trial
- chronic kidney disease
- newly diagnosed
- juvenile idiopathic arthritis
- peritoneal dialysis
- skeletal muscle
- breast cancer risk