In chronic spontaneous urticaria, increased Galectin-9 expression on basophils and eosinophils is linked to high disease activity, endotype-specific markers, and response to omalizumab treatment.
Jiang JiMinhui TangYue ZhaoChuqiao ZhangYu ShenBin ZhouCuiping LiuMarcus MaurerQingqing JiaoPublished in: Allergy (2024)
Our findings demonstrate a previously unrecognized involvement of the Gal-9/TIM-3 pathway in the pathogenesis CSU and call for studies that explore its relevance.