Evaluation of Neonatal and Paediatric Vancomycin Pharmacokinetic Models and the Impact of Maturation and Serum Creatinine Covariates in a Large Multicentre Data Set.
Jasmine H HughesDominic M H TongJonathan D FaldaszAdam FrymoyerRon J KeizerPublished in: Clinical pharmacokinetics (2022)
Several available pharmacokinetic models are suitable for MIPD in infants and neonates. Availability and accuracy of model covariates for patients will be important for guiding dose decision-making.
Keyphrases
- end stage renal disease
- decision making
- ejection fraction
- newly diagnosed
- chronic kidney disease
- emergency department
- intensive care unit
- clinical trial
- prognostic factors
- peritoneal dialysis
- randomized controlled trial
- electronic health record
- methicillin resistant staphylococcus aureus
- study protocol
- big data
- cross sectional
- staphylococcus aureus
- machine learning
- artificial intelligence
- low birth weight
- metabolic syndrome
- data analysis