Perioperative Management of Immunosuppressive Medications in Rheumatic Disease Patients Undergoing Arthroscopy.
Kinjal D VasavadaLaith M JazrawiJonathan SamuelsPublished in: Current reviews in musculoskeletal medicine (2021)
Utilization rates of arthroscopic surgery in patients with rheumatic diseases are on the rise, as immunosuppressive treatment options enable them to lead more active lives and hence experience more injuries. Physicians regularly manage patients' glucocorticoids and conventional synthetic and biologic disease modifying antirheumatic drugs around the time of orthopedic surgery, aiming to minimize infection risk while optimizing disease control. However, there is a paucity of randomized controlled trial data for orthopedic surgery-and specifically nothing in the literature pertaining to arthroscopic surgery. Recent guidelines for rheumatic disease patients undergoing elective total hip and knee arthroplasty recommend that most immunosuppressive medications should be held perioperatively, citing the high-risk profile of arthroplasty cases and arthroplasty patients. While 2017 societal guidelines for perioperative immunosuppression during arthroplasty currently serve as a guide for physicians, they may not be applicable to arthroscopy. The less aggressive arthroscopic surgeries span a broader range of patient ages and risk profiles, indications for surgery, and procedural complexity and associated risks. Given these considerations, the majority of routine arthroscopic patients may not require holding of their immunosuppressive medications in the perioperative period.
Keyphrases
- patients undergoing
- minimally invasive
- end stage renal disease
- randomized controlled trial
- coronary artery bypass
- rheumatoid arthritis
- newly diagnosed
- ejection fraction
- chronic kidney disease
- primary care
- peritoneal dialysis
- prognostic factors
- clinical practice
- cardiac surgery
- risk assessment
- patient reported outcomes
- machine learning
- disease activity
- percutaneous coronary intervention
- electronic health record
- acute kidney injury
- rotator cuff
- human health
- artificial intelligence
- anterior cruciate ligament reconstruction
- rheumatoid arthritis patients