Burn-related chronic neuropathic pain can contribute to a decreased quality of life. When medical and pharmacologic therapies prove ineffective, patients should undergo evaluation for surgical intervention, consisting of a detailed physical examination and elective diagnostic nerve block, to identify an anatomic cause of pain. Based on symptoms and physical examination findings, particularly Tinel's sign, treatments can vary, including a trial of laser therapies, fat grafting, or nerve surgeries (nerve decompression, neuroma excision, targeted muscle reinnervation, regenerative peripheral nerve interfaces, and vascularized denervated muscle targets). It is essential to counsel patients to establish appropriate expectations prior to treatment with a multidisciplinary team.
Keyphrases
- neuropathic pain
- peripheral nerve
- end stage renal disease
- ejection fraction
- spinal cord injury
- chronic kidney disease
- randomized controlled trial
- stem cells
- spinal cord
- chronic pain
- healthcare
- physical activity
- skeletal muscle
- peritoneal dialysis
- prognostic factors
- clinical trial
- pain management
- adipose tissue
- fatty acid
- patient reported outcomes
- high resolution
- drug delivery
- wound healing
- phase iii
- combination therapy
- smoking cessation