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Gene co-expression networks associated with carcass traits reveal new pathways for muscle and fat deposition in Nelore cattle.

Bárbara Silva-VignatoLuiz L CoutinhoMirele D PoletiAline S M CesarCristina T MoncauLuciana C A RegitanoJúlio C C Balieiro
Published in: BMC genomics (2019)
With this study, we verified that inflammation and immune response pathways modulate the BFT trait. Energy and lipid metabolism pathways, highlighting fatty acid metabolism, were the central pathways associated with REA. Some genes, as RSAD2, EIF2AK2, ACAT1, and ACSL1 were considered as putative candidate related to these traits. Altogether these results allow us to a better comprehension of the molecular mechanisms that lead to muscle and fat deposition in bovine.
Keyphrases
  • genome wide
  • fatty acid
  • immune response
  • dna methylation
  • adipose tissue
  • skeletal muscle
  • oxidative stress
  • poor prognosis
  • copy number
  • gene expression
  • genome wide identification
  • inflammatory response
  • drug induced