Evaluation of droplet digital polymerase chain reaction by detecting cell-free deoxyribonucleic acid in pleural effusion for the diagnosis of tuberculous pleurisy: a multicentre cohort study.

Fudong XuWeili DuChengjun LiYe LiZhihui LiWenge HanHuimin LiJianqin LiangDongmei ZhaoXinting YangFeng WangChaolian LongXuya XingJing TanNana ZhangZuyu SunNanying Che

Published in: Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases (2024)

The performance of cf-ddPCR is superior to Culture, Xpert, Ultra, and real-time PCR, indicating that improved diagnostic accuracy can be anticipated by incorporating this new assay.

Keyphrases

cell free
real time pcr
high throughput
cystic fibrosis
circulating tumor
single cell
study protocol
high resolution
clinical trial
cross sectional
randomized controlled trial
mass spectrometry