Epigenome wide association study of response to methotrexate in early rheumatoid arthritis patients.

Helen R GosseltCostanza L VallergaPooja R MandaviyaErik LubbertsJohanna M W HazesRobert de JongeSandra G Heil

Published in: PloS one (2021)

No baseline genome-wide significant differences were identified as biomarker for MTX (combination) therapy response; hence meta-analyses are required.

Keyphrases

combination therapy
rheumatoid arthritis patients
meta analyses
genome wide
dna methylation
systematic review
disease activity
randomized controlled trial
high dose
rheumatoid arthritis