Astaxanthin alleviates cerebral edema by modulating NKCC1 and AQP4 expression after traumatic brain injury in mice.
Mingkun ZhangZhenwen CuiHua CuiYang CaoChunlong ZhongYong WangPublished in: BMC neuroscience (2016)
Our data suggest that astaxanthin reduces TBI-related injury in brain tissue by ameliorating AQP4/NKCC1-mediated cerebral edema and that NKCC1 contributes to the upregulation of AQP4 after TBI.
Keyphrases
- traumatic brain injury
- poor prognosis
- subarachnoid hemorrhage
- cerebral ischemia
- severe traumatic brain injury
- signaling pathway
- mild traumatic brain injury
- electronic health record
- long non coding rna
- white matter
- cell proliferation
- resting state
- brain injury
- high fat diet induced
- cerebral blood flow
- multiple sclerosis
- blood brain barrier
- metabolic syndrome
- type diabetes
- adipose tissue
- functional connectivity
- skeletal muscle
- artificial intelligence
- drug induced