Comparative analysis of the DNA methylation landscape in CD4, CD8, and B memory lineages.
Ze ZhangRondi A ButlerDevin C KoestlerShelby Bell-GlennGayathri WarrierAnnette M MolinaroBrock C ChristensenJohn K WienckeKarl T KelseyLucas A SalasPublished in: Clinical epigenetics (2022)
Our data suggest that epigenetic alterations are widespread and essential in generating human lymphocyte memory. Unique profiles are involved in methylation changes that accompany memory genesis in the three subtypes of lymphocytes.