Health Effects of Grape Seed and Skin Extracts and Their Influence on Biochemical Markers.
Lenka SochorovaBozena PrusovaMartina CebovaTunde JurikovaJiri MlcekAnna AdámkováŠárka NedomováMojmir BaronJiri SochorPublished in: Molecules (Basel, Switzerland) (2020)
This review is focused on the study of the effects of grape seed and skin extract (GSSE) on human health. GSSE contains high concentrations of important polyphenolic substances with high biological activity. This review is a summary of studies that investigate the effects of GSSE on diabetes mellitus, cardiovascular disease and cancer, its neuroprotective effect, and its effects on the gastrointestinal tract and other health complications related to these diseases. The results of the studies confirm that the anti-inflammatory, antiapoptotic, and pro-proliferative effects of "Vitis vinifera L." seed extract reduce the level of oxidative stress and improve the overall lipid metabolism.
Keyphrases
- anti inflammatory
- human health
- oxidative stress
- risk assessment
- cardiovascular disease
- soft tissue
- case control
- climate change
- healthcare
- public health
- papillary thyroid
- wound healing
- dna damage
- mental health
- ischemia reperfusion injury
- metabolic syndrome
- drinking water
- risk factors
- diabetic rats
- induced apoptosis
- squamous cell carcinoma
- health information
- squamous cell
- insulin resistance
- blood brain barrier
- skeletal muscle
- fatty acid
- endoplasmic reticulum stress
- cerebral ischemia
- drug induced
- heat shock