Reduction of IL-6 gene expression in human adipose tissue after sleeve gastrectomy surgery.
Isabel CasimiroErin C HanlonJeremy WhiteAvelino De LeonRuby RossKatiannah MoiseMatthew PironMatthew J BradyPublished in: Obesity science & practice (2020)
Early weight loss after VSG is associated with a reduction in adipocyte size and a decline in IL-6 gene expression in local adipose tissue. Macrophage infiltration and crownlike density structures persist in adipose tissue from tissues impacted by excess body weight 3 months after VSG-induced weight loss.
Keyphrases
- adipose tissue
- gene expression
- weight loss
- body weight
- insulin resistance
- bariatric surgery
- high fat diet
- dna methylation
- endothelial cells
- roux en y gastric bypass
- gastric bypass
- high glucose
- minimally invasive
- diabetic rats
- coronary artery bypass
- high resolution
- type diabetes
- induced pluripotent stem cells
- pluripotent stem cells
- oxidative stress
- obese patients
- coronary artery disease
- fatty acid
- atrial fibrillation
- percutaneous coronary intervention