Insulin increases cholesterol uptake, lipid droplet content, and apolipoprotein B secretion in CaCo-2 cells by upregulating SR-BI via a PI3K, AKT, and mTOR-dependent pathway.

Marcela FuentesNicolás SantanderVíctor A Cortés

Published in: Journal of cellular biochemistry (2018)

insulin promotes cholesterol uptake, intracellular lipid store, and apo B-containing lipoproteins secretion by SR-BI-dependent mechanisms in a model of human intestinal epithelium.

Keyphrases

pi k akt
cell cycle arrest
signaling pathway
type diabetes
cell proliferation
induced apoptosis
cell death
low density lipoprotein
endothelial cells
glycemic control
fatty acid
single cell
induced pluripotent stem cells
pluripotent stem cells
metabolic syndrome
weight loss