Predicting opioid-induced oversedation in hospitalised patients: a multicentre observational study.
John GarrettAnneliese VanstonGerald OgolaBriget da GracaCindy CassityMaria A KouznetsovaLauren R HallTaoran QiuPublished in: BMJ open (2021)
The ORC risk score identifies patients at high risk for OIRD or oversedation from routinely collected data, enabling targeted monitoring for early detection and intervention. It can also be applied to preventive strategies-for example, clinical decision support offered when concurrent prescriptions for opioids and other sedating medications are entered that shows how the chosen combination impacts the patient's risk.
Keyphrases
- end stage renal disease
- ejection fraction
- clinical decision support
- chronic kidney disease
- newly diagnosed
- randomized controlled trial
- prognostic factors
- clinical trial
- chronic pain
- peritoneal dialysis
- electronic health record
- pain management
- squamous cell carcinoma
- oxidative stress
- dna methylation
- machine learning
- cross sectional
- rectal cancer
- diabetic rats
- high glucose
- locally advanced
- artificial intelligence
- endothelial cells
- stress induced
- double blind