Role of kidney function on Nrf2 mRNA levels in type 2 diabetes.

Belinda SpotoCristina PolitiMaurizio PostorinoRosa Maria ParlongoAlessandra TestaGiovanni Luigi TripepiFrancesca MallamaciCarmine Zoccali

Published in: BMJ open diabetes research & care (2024)

The observed dysregulation in the Nrf2-Keap1 axis and the unique expression pattern of miRNA30e-5p in DKD underscore the need for more focused research in this domain that can help identify novel intervention strategies for DKD in patients with type 2 diabetes.

Keyphrases

type diabetes
oxidative stress
poor prognosis
randomized controlled trial
binding protein
cardiovascular disease
glycemic control
insulin resistance
long non coding rna
protein protein
skeletal muscle