Impact of intravenous fish oil on omega-3 fatty acids and their derived lipid metabolites in patients with parenteral nutrition.

Karsten-Henrich WeylandtMirjam KarberYanan XiaoIngrid W ZhangSophie PevnyElisabeth BlüthnerClemens von SchackyMichael RotheWolf H SchunckUlrich F Pape

Published in: JPEN. Journal of parenteral and enteral nutrition (2022)

This study shows that fish oil-containing PN leads to primarily CYP and LOX-dependent n-3 PUFA derived inflammation dampening oxylipins (n-3 IDOs) arising from EPA and DHA. Within this short (16 week) study there were no significant changes in inflammation and clinical readout parameters. This article is protected by copyright. All rights reserved.

Keyphrases

fatty acid
oxidative stress
randomized controlled trial
ms ms
clinical trial
study protocol