Gut feeling: randomized controlled trials of probiotics for the treatment of clinical depression: Systematic review and meta-analysis.

Viktoriya L NikolovaSyed Yawar ZaidiAllan H YoungAnthony J CleareJames M Stone

Published in: Therapeutic advances in psychopharmacology (2019)

There is limited evidence for the efficacy of probiotics in depression at present, although there may be a beneficial effect of probiotics on depressive symptoms when administered in addition to antidepressants. Further studies are required to investigate this and explore potential mechanisms.

Keyphrases

depressive symptoms
sleep quality
randomized controlled trial
social support
major depressive disorder
systematic review
study protocol
climate change
meta analyses
double blind