Interindividual differences of dietary fat-inducible Mest in white adipose tissue of C57BL/6J mice are not heritable.
Rea Victoria P Anunciado-KozaHaifeng YinCrystal L BilodeauDiana CookeGene P AblesSergey RyzhovRobert A KozaPublished in: Obesity (Silver Spring, Md.) (2024)
Disparity of HFD-induced Mest in mice is not heritable but, rather, is reestablished during each generation and remains fixed from an early age to adulthood. Short-term HFD feeding reveals variation of WAT Mest expression within isogenic mice that is positively associated with the development of obesity.