Low CREBBP expression is associated with adverse long-term outcomes in paediatric acute lymphoblastic leukaemia.
Chao GaoRui-Dong ZhangShu-Guang LiuXiao-Xi ZhaoLei CuiZhi-Xia YueWei-Jing LiZhen-Ping ChenZhi-Gang LiQing RaoMin WangHu-Yong ZhengJian-Xiang WangPublished in: European journal of haematology (2017)
These findings indicate that low-CREBBP is predictive of unfavourable outcomes; thus, a more intensive treatment protocol is necessitated for standard-risk patients with insufficient CREBBP and that a specific target therapy is necessitated for high-risk patients.
Keyphrases
- end stage renal disease
- newly diagnosed
- ejection fraction
- chronic kidney disease
- emergency department
- randomized controlled trial
- poor prognosis
- intensive care unit
- prognostic factors
- type diabetes
- mesenchymal stem cells
- hepatitis b virus
- skeletal muscle
- respiratory failure
- patient reported outcomes
- weight loss
- glycemic control
- insulin resistance
- patient reported