The Effect of Combined Oral Contraceptive Pills on Beclin-1 and LC3B Transcript Levels in Ovarian Endometrioma.
Wanwisa WaiyaputOngarj BovornsakulvongSrithean LertvikoolAreepan SophonsritsukPublished in: BioMed research international (2021)
Oral COC pills for 6 weeks continuously before surgery decreased the eutopic endometrial expression (mRNA) of the BECN1 gene compared to those from healthy normal women and nontreated patients with an endometriotic cyst. The change in the expression of autophagy-related genes was more distinct in eutopic than ectopic endometria. This trial is registered with TCTR20170720002. Registered and enrolled the first patient on 20 July 2017.
Keyphrases
- poor prognosis
- binding protein
- minimally invasive
- cell death
- oxidative stress
- polycystic ovary syndrome
- coronary artery bypass
- genome wide
- clinical trial
- signaling pathway
- endoplasmic reticulum stress
- mass spectrometry
- phase iii
- randomized controlled trial
- long non coding rna
- gene expression
- copy number
- adipose tissue
- dna methylation
- type diabetes
- metabolic syndrome
- acute coronary syndrome
- breast cancer risk
- double blind