Bio-derived hydroxystearic acid ameliorates skin age spots and conspicuous pores.

Schuetz RolfA V RawlingsE WandelerE JacksonS TrevisanJ-M MonneuseI BendikM MassironiD Imfeld

Published in: International journal of cosmetic science (2019)

HSA acts as a PPARα agonist to reduce the signs of age spots and conspicuous pores by significantly modulating the expression of p53, SBC, MMP-1 and collagen together with major changes in secreted proteins that modify keratinocyte, melanocyte and fibroblast cell behavior.

Keyphrases

wound healing
poor prognosis
single cell
cell therapy
signaling pathway
stem cells
insulin resistance
mouse model
soft tissue
binding protein
metabolic syndrome
fatty acid
long non coding rna
mesenchymal stem cells
bone marrow