Randomised, controlled, feasibility trial comparing vasopressor infusion administered via peripheral cannula versus central venous catheter for critically ill adults: A study protocol.
Stacey WattsYogesh ApteThomas HollandApril HattAlison CraswellFrances Fengzhi LinAlexis TabahRobert WareJoshua ByrnesChristopher AnsteyGerben KeijzersMahesh RamananPublished in: PloS one (2024)
VIPCA is a feasibility RCT whose outcomes will inform the feasibility and design of a multicentre Phase-3 trial comparing routes of vasopressor delivery. The exploratory economic analysis will provide input data for the full health economic analysis which will accompany any future Phase-3 RCT.
Keyphrases
- study protocol
- clinical trial
- randomized controlled trial
- healthcare
- public health
- low dose
- mental health
- open label
- extracorporeal membrane oxygenation
- phase iii
- metabolic syndrome
- electronic health record
- intensive care unit
- cross sectional
- climate change
- obstructive sleep apnea
- deep learning
- social media
- artificial intelligence
- skeletal muscle
- health promotion