Modulation of autophagy by an innovative phytocosmetic preparation (Myrothamnus flabelifolia and Coffea arabica) in human fibroblasts and its effects in a clinical randomized placebo-controlled trial.
Rafael C BiscaroLilian MussiBianca SufiGiovana PadovaniFlavio B Camargo JuniorWagner V MagalhãesLuiz Claudio Di StasiPublished in: Journal of cosmetic dermatology (2022)
The phytocosmetic preparation containing Myrothamnus flabellifolia leaf and Coffea arabica seed modulated ubiquitin-proteasome and autophagy process, representing an innovative and safe herbal preparation to improve skin features, mainly acting as skin anti-aging and lightening agent.
Keyphrases
- double blind
- molecularly imprinted
- cell death
- endoplasmic reticulum stress
- endothelial cells
- signaling pathway
- oxidative stress
- soft tissue
- open label
- wound healing
- placebo controlled
- clinical trial
- phase iii
- randomized controlled trial
- phase ii
- induced pluripotent stem cells
- mass spectrometry
- high resolution
- pluripotent stem cells
- solid phase extraction