Systematic Review and Quantitative Data Synthesis of Peripheral Blood Mononuclear Cell Transcriptomics Reveals Consensus Gene Expression Changes in Response to a High Fat Meal.
Aimee L DordevicGary WilliamsonPublished in: Molecular nutrition & food research (2023)
Despite differences in study design, common gene changes are identified in PBMCs following a high fat meal. These common genes and processes will facilitate definition of the postprandial transcriptome as part of the overall postcibalome, linking all molecules and processes that change in the blood after a meal.
Keyphrases
- peripheral blood
- single cell
- gene expression
- systematic review
- genome wide
- rna seq
- dna methylation
- genome wide identification
- meta analyses
- copy number
- cell therapy
- electronic health record
- high resolution
- randomized controlled trial
- blood glucose
- big data
- genome wide analysis
- blood pressure
- machine learning
- type diabetes
- clinical practice
- transcription factor
- adipose tissue
- deep learning
- metabolic syndrome
- mass spectrometry
- skeletal muscle