ENCoRE: an efficient software for CRISPR screens identifies new players in extrinsic apoptosis.
Dietrich TrümbachSusanne PfeifferManuel PoppeHagen ScherbSebastian DollWolfgang WurstJoel A SchickPublished in: BMC genomics (2017)
In summary, this software enables bench scientists with sensitive data or without access to informatic cores to rapidly interpret results from large scale experiments resulting from pooled CRISPR/Cas9 library screens.
Keyphrases
- genome wide
- crispr cas
- genome editing
- data analysis
- dna methylation
- high throughput
- oxidative stress
- endoplasmic reticulum stress
- cell cycle arrest
- electronic health record
- cell death
- big data
- randomized controlled trial
- machine learning
- phase iii
- cell proliferation
- single cell
- signaling pathway
- study protocol
- open label